Autor: |
De La Hera, A., Toribio, M. L., Marcos, M. A. R., Marquez, C., Martinez-A, C. |
Předmět: |
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Zdroj: |
Scandinavian Journal of Immunology; Dec1986, Vol. 24 Issue 6, p637-642, 6p |
Abstrakt: |
This article focuses on T cell network early in the intrathymic differentiation. T-cell recognition requires direct cell-cell interactions mediated by major histocompatibility complex (MHC)-restricted &aalpha; and &bbeta; heterodimeric receptors in association with a constant protein complex termed. Interleukin-2 promotes growth and maturation of T cells upon binding to high affinity receptors. Thus, developmental analyses of T cell function are essential to gain insight into the mechanisms for selection of available repertoires, one of the central problems in immunology. |
Databáze: |
Complementary Index |
Externí odkaz: |
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