Impact of ROI Size on the Accuracy of Noise Measurement in CT on Computational and ACR Phantoms.

Autor: Anam, Choirul, Triadyaksa, Pandji, Naufal, Ariij, Arifin, Zaenal, Muhlisin, Zaenul, Setiawati, Evi, Budi, Wahyu Setia
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Zdroj: Journal of Biomedical Physics & Engineering; Aug2022, Vol. 12 Issue 4, p359-368, 10p
Abstrakt: Background: The effect of region of interest (ROI) size variation on producing accurate noise levels is not yet studied. Objective: This study aimed to evaluate the influence of ROI sizes on the accuracy of noise measurement in computed tomography (CT) by using images of a computational and American College of Radiology (ACR) phantoms. Material and Methods: In this experimental study, two phantoms were used, including computational and ACR phantoms. A computational phantom was developed by using Matlab R215a software (Mathworks Inc., Natick, MA Natick, MA) with a homogeneously +100 Hounsfield Unit (HU) value and an added-Gaussian noise with various levels of 5, 10, 25, 50, 75, and 100 HU. The ACR phantom was scanned with a Philips MX-16 slice CT scanner in different slice thicknesses of 1.5, 3, 5, and 7 mm to obtain noise variation. Noise measurement was conducted at the center of the phantom images and four locations close to the edge of the phantom images using different ROI sizes from 3×3 to 41×41 pixels, with an increased size of 2×2 pixels. Results: The use of a minimum ROI size of 21×21 pixels shows noise in the range of ±5% ground truth noise. The measured noise increases above the ±5% range if the used ROI is smaller than 21×21 pixels. Conclusion: A minimum acceptable ROI size is required to maintain the accuracy of noise measurement with a size of 21×21 pixels. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index