| Autor: |
Tidke, Vishwamber A., Patwari, Shivaji B., Survase, Avinash A., Kadam, Avdhut D., Pokalwar, Rajkumar U. |
| Předmět: |
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| Zdroj: |
Chemistry & Biology Interface; May/Jun2022, Vol. 12 Issue 3, p69-76, 8p |
| Abstrakt: |
A novel series of diethyl (hydroxy(2-morpholinoquinolin-3-yl) methyl) phosphonates have been synthesized by the reaction of 2-chloroquinolin-3-carbaldehydes, triethylphosphite and morpholine in high yields. All the novel series of diethyl (hydroxy(2-morpholinoquinolin-3-yl) methyl) phosphonate derivatives have been characterized by IR, 1HNMR and mass spectroscopy. All novel synthesized compounds have been screened for antimicrobial activity against bacterial strains Staphylococcus aureus (NCIM-2654), Bacillus subtilis (NCIM-2635), Escherichia coli (NCIM-2832) and Pseudomonas aeruginosa (NCIM- 5032). These novel synthesized compounds show moderate to good antibacterial activity Gram positive and Gram-negative pathogenic strains. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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