Facile synthesis, antimicrobial, and anti‐inflammatory activities of novel isoxazolyl imidazo[1,2‐b]isoxazoles.

Autor:	Rama Krishna, Saini, Nagaraju, Dharavath, Srinivas Reddy, Malladi, Rajanarendar, Eligeti
Předmět:	IMIDAZOPYRIDINES ISOXAZOLES ANTI-inflammatory agents CUPROUS iodide CHEMICAL synthesis RING formation (Chemistry)
Zdroj:	Journal of Heterocyclic Chemistry; Aug2022, Vol. 59 Issue 8, p1341-1349, 9p
Abstrakt:	A copper iodide promoted cyclization for the synthesis of isoxazolyl imidazo[1,2‐b]isoxazoles 3 in a one‐pot procedure has been investigated by interaction of 3‐aminoisoxazole 1 with nitrostyrylisoxazoles 2 under aerial oxidation condition. The newly synthesized compounds 3a–l were screened for their in vitro antimicrobial and anti‐inflammatory activities. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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