New Terpenoids from the Corticioid Fungus Punctularia atropurpurascens and their Antimycobacterial Evaluation#.

Autor: Acero, Daniel, Khan, Firoz Shah Tuglak, Medina-Ortiz, Abraham J., Rivero-Cruz, Isabel, Raja, Huzefa A., Flores-Bocanegra, Laura, Fajardo-Hernández, Carlos A., Wan, Baojie, Franzblau, Scott G., Hematian, Shabnam, Figueroa, Mario
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Zdroj: Planta Medica; Aug2022, Vol. 88 Issue 9/10, p729-734, 6p
Abstrakt: Chemical investigation of Punctularia atropurpurascens strain HM1 (Punctulariaceae), a corticioid isolated from a decorticated piece of Quercus bark collected in Bosque de Tlalpan, Mexico City, led to the isolation of a new drimane, 1- α -hydroxy-isodrimenine (1) and a new tetrahydroxy kauranol, 16-hydroxy-phlebia- nor -kauranol (2), together with the known N -phenylacetamide (3). Structures of all compounds were elucidated by spectroscopic and spectrometric methods, and the absolute configuration of 1 and 2 was confirmed via single-crystal X-ray crystallography. The isolated compounds showed modest antimycobacterial activity. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index