SECISBP2L-Mediated Selenoprotein Synthesis Is Essential for Autonomous Regulation of Oligodendrocyte Differentiation.

Autor: Zhong-Min Dai, Wei Guo, Dan Yu, Xiao-Jing Zhu, Shuhui Sun, Hao Huang, Min Jiang, Binghua Xie, Zunyi Zhang, Mengsheng Qiu
Předmět:
Zdroj: Journal of Neuroscience; 7/27/2022, Vol. 42 Issue 30, p5860-5869, 10p
Abstrakt: The article presents the discussion on thyroid hormone (TH) controlling the timely differentiation of oligodendrocytes (OLs). Topics include discovered the SECISBP2L being highly expressed in differentiating OLs and required for DIO2 translation; and excess TH suppressing the production of thyrotropin-releasing hormone from the hypothalamus.
Databáze: Complementary Index