| Autor: |
Bangash, Arzoo Gul, Tabassum, Shazia, Afridi, Fauzia, Zahoor, Farnaz |
| Předmět: |
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| Zdroj: |
Journal of Medical Sciences (1997-3438); Apr2022, Vol. 30 Issue 2, p117-120, 4p |
| Abstrakt: |
Objective: To find out the outcomes of pregnancy and safety of chemotherapeutic regimen in women who conceived after chemotherapy for the treatment of Gestational Trophoblastic Neoplasia. Materials and Methods: A Prospective cohort study was done at the Department of Obstetrics and Gynecology, Hayatabad Medical Complex, Peshawar. Ninety women were followed up for pregnancy outcomes after being diagnosed with Gestational Trophoblastic Neoplasia and treated with standard chemotherapeutic regimens between June 2005-2014. After treatment, patients were followed up for a period of five years. The patients' demographic profile, FIGO score, type of chemotherapy, treatment, and pregnancy outcomes were recorded on predesigned Performa and a computerized record was kept. Data analysis was done through SPSS-16. Results: The mean age of patients was 28.2 years (±12.5) and the mean parity was 3.39 (±1.49). Out of 90 patients diagnosed with Gestational Trophoblastic Neoplasia, 59 (65.6%) patients were of low risk and 31 (34.4 %) were in the high-risk category. Overall survival was 100% after chemotherapy in the low-risk category and 70.58% in the high-risk category. The pregnancy rate among women with the desire to conceive was 97%. The term live birth in 42 pregnancies was 85.7%, without any congenital abnormality. Five (10.2%) women had miscarriages, 1 woman (2%) had a repeat molar pregnancy, and 4 women experienced live twin birth after chemotherapy. Conclusions: Women who underwent treatment for Gestational Trophoblastic Neoplasia can be assured positively about their pregnancy outcomes and fertility prospects in the future. Chemotherapy regimens currently used globally are highly effective and preserve fertility. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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