| Autor: |
Darooneh, Amir Hossein, Kohandel, Mohammad |
| Předmět: |
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| Zdroj: |
Frontiers in Physiology; 7/1/2022, Vol. 13, p1-11, 11p |
| Abstrakt: |
Metastasis is the process by which cancer cells acquire the capability to leave the primary tumor and travel to distant sites. Recent experiments have suggested that the epithelial-mesenchymal transition can regulate invasion and metastasis. Another possible scenario is the collective motion of cells. Recent studies have also proposed a jamming-unjamming transition for epithelial cells based on physical forces. Here, we assume that there exists a short-range chemical attraction between cancer cells and employ the Brownian dynamics to simulate tumor growth. Applying the network analysis, we suggest three possible phases for a given tumor and study the transition between these phases by adjusting the attraction strength. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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