| Autor: |
Smit, Ellen, Semba, Richard D., Pilibosian, Erin, Vlahov, David, Tun, Waimar, Purvis, Lisa, Tang, Alice M. |
| Předmět: |
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| Zdroj: |
AIDS Patient Care & STDs; Jan2005, Vol. 19 Issue 1, p19-30, 12p |
| Abstrakt: |
We determined anthropometric measurements (including height, weight, circumferences, andskinfolds) and self-reported symptoms related to body habitus changes in 324 HIV-seropositiveand HIV-seronegative inner city injection drug users (IDUs) who participated in a substudyfrom the ALIVE (AIDS Linked to Intravenous Experiences) cohort. Participants who reportedlipoatrophy in body parts had consistently lower anthropometric measurements andthose reporting adiposity had correspondingly higher anthropometric measurements than participantswho did not report these changes. Peripheral lipoatrophy was more common amongall HIV-seropositive than HIV-seronegative participants, however, it was not associated withhighly active antiretroviral therapy (HAART) (39% HIV-seronegatives; 58% HIV-seropositivenot receiving HIV treatment [No Tx]; 49% HAART,= 0.04). Central adiposity was more commonamong HAART (52%) than No Tx (26.6%) and HIV-seronegative (42%) participants (=0.001). However, waist circumference, while somewhat higher among HAART than No Tx participants,did not differ significantly from HIV-seronegative participants (85.2 cm HIV-seronegatives;83.3 cm No Tx; 85.8 cm HAART). A large proportion of those who reported peripherallipoatrophy also reported central lipoatrophy (76.9% HIV-seronegatives; 69.6% No Tx; 66.2%HAART). A large proportion of those who reported central adiposity also reported adiposity ofthe peripheral sites (88.1% HIV seronegatives; 66.7% No Tx; 74.3% HAART). The combinationof lipoatrophy and adiposity was associated with HAART treatment (6% HIV-seronegatives;3% No Tx; 16% HAART,= 0.002), but may be driven by the association with adiposity. Thesedata suggest validity of self-reports for body habitus changes among injection drug users. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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