Studies on Haematological and some Serum Biochemical Changes by Oral Administration of Gossypol from Cotton Seed Cake in Rabbits.

Autor: Mahmood, Altaf, Khan, Muhammad Athar, Parveen, Saima, Hussain, Tanveer, Azad, Ayesha
Předmět:
Zdroj: Sarhad Journal of Agriculture; Jun2022, Vol. 38 Issue 2, p417-421, 5p
Abstrakt: In present experimental study, haematological and some serum biochemical alterations were explored in six months old commercially raised eight female rabbits after oral administration of gossypol. Cotton seed cake with 0.25% free gossypol concentration was daily given to each rabbit at the rate of 4 grams per kg live weight for entire experiment period of 60 days. Analysis of fortnightly collected blood specimens revealed significantly (p <0.05) decreased hematocrit, total red blood cell count, mean corpuscular volume, haemoglobin concentration and inorganic phosphorous level of serum whereas significantly (p < 0.05) decreased mean corpuscular haemoglobin, red cell distribution width, mean corpuscular haemoglobin concentration, total white cell count, monocytes and lymphocytes. The level of serum calcium and granulocytes exhibited non significant (p > 0.05) difference. It was concluded that gossypol exposure induces anaemia, microsytosis and hypophosphetaemia. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index