| Autor: |
Yang, Shang-Yu, Fang, Chi-Jung, Chen, Yu-Wen, Chen, Wan-Ping, Lee, Li-Ya, Chen, Chin-Chu, Lin, Yen-You, Liu, Shan-Chi, Tsai, Chun-Hao, Huang, Wei-Chien, Wu, Yang-Chang, Tang, Chih-Hsin |
| Zdroj: |
Nutrients; Jul2022, Vol. 14 Issue 13, p2605-N.PAG, 10p |
| Abstrakt: |
Osteoarthritis (OA) is an age-related disorder that affects the joints and causes functional disability. Hericium erinaceus is a large edible mushroom with several known medicinal functions. However, the therapeutic effects of H. erinaceus in OA are unknown. In this study, data from Sprague-Dawley rats with knee OA induced by anterior cruciate ligament transection (ACLT) indicated that H. erinaceus mycelium improves ACLT-induced weight-bearing asymmetry and minimizes pain. ACLT-induced increases in articular cartilage degradation and bone erosion were significantly reduced by treatment with H. erinaceus mycelium. In addition, H. erinaceus mycelium reduced the synthesis of proinflammatory cytokines interleukin-1β and tumor necrosis factor-α in OA cartilage and synovium. H. erinaceus mycelium shows promise as a functional food in the treatment of OA. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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