Autor: |
Djaló, Mariama, Silva, Maria J. S. A., Faustino, Hélio, Pinto, Sandra N., Mendonça, Ricardo, Gois, Pedro M. P. |
Předmět: |
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Zdroj: |
Chemical Communications; 7/21/2022, Vol. 58 Issue 57, p7928-7931, 4p |
Abstrakt: |
The site-selective chemical appendage of multiple functionalities on a native peptide backbone is a highly demanding and complex tool of modern chemical biology. Here, novel NHS-activated acrylates were designed to hold various payloads in a single bioconjugation handle that is able to site-selectively and orthogonally target the N-terminal cysteine of peptides. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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