| Autor: |
Laaksonen, David E., Lindström, Jaana, Lakka, Timo A., Eriksson, Johan G., Niskanen, Leo, Wikström, Katja, Aunola, Sirkka, Keinänen-Kiukaanniemi, Sirkka, Laakso, Mauri, Valle, Timo T., Ilanne-Parikka, Pirjo, Louheranta, Anne, Hämäläinen, Helena, Rastas, Merja, Salminen, Virpi, Cepaitis, Zygimantas, Hakumäki, Martti, Kaikkonen, Hannu, Härkönen, Pirjo, Sundvall, Jouko |
| Předmět: |
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| Zdroj: |
Diabetes; Jan2005, Vol. 54 Issue 1, p158-165, 8p, 3 Charts, 2 Graphs |
| Abstrakt: |
Clinical trials have demonstrated that lifestyle changes can prevent type 2 diabetes, but the importance of leisure-time physical activity (LTPA) is still unclear. We carried out post hoc analyses on the role of LTPA in preventing type 2 diabetes in 487 men and women with impaired glucose tolerance who had completed 12-month LTPA questionnaires. The subjects were participants in the Finnish Diabetes Prevention Study, a randomized controlled trial of lifestyle changes including diet, weight loss, and LTPA. There were 107 new cases of diabetes during the 4.1-year follow-up period. Individuals who increased moderate-to-vigorous LTPA or strenuous, structured LTPA the most were 63-65% less likely to develop diabetes. Adjustment for changes in diet and body weight during the study attenuated the association somewhat (upper versus lower third: moderate-to-vigorous LTPA, relative risk 0.51, 95% CI 0.26-0.97; strenuous, structured LTPA, 0.63, 0.35-1.13). Low-intensity and lifestyle LTPA and walking also conferred benefits, consistent with the finding that the change in total LTPA (upper versus lower third: 0.34, 0.19-0.62) was the most strongly associated with incident diabetes. Thus increasing physical activity may substantially reduce the incidence of type 2 diabetes in high-risk individuals. Diabetes 54:158-165, 2005 [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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