Changes in macular thickness measurements repeatability with age using Cirrus Fourier‐domain optical coherence.

Autor: PINILLA, I, GARCIA‐MARTIN, E, IDOIPE, M, FUENTES, L, SANCHEZ‐CANO, A, LOPEZ DE LA FUENTE, C, FUERTES, MI
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Zdroj: Acta Ophthalmologica (1755375X); Sep2012 Supplement S249, Vol. 90, p0-0, 1p
Abstrakt: Purpose To test the intrassession reproducibility of retinal thickness measurements using Cirrus Fourier‐domain optical coherence tomography (OCT). To evaluate if there is any relation between macular measurements repeatability and age of the studied subject. Methods Two hundred and nine of 209 healthy subjects underwent three macular 512x128 volume cube centered on the fovea done by the same experienced examiner using Cirrus HD OCT (Carl Zeiss, USA). Descriptive statistics, analysis of variance, intraclass correlation coefficients (ICC), and coefficients of variation (COV) were calculated for the 9 macular areas described by the Early Treatment Diabetic Retinopathy Study (ETDRS) in the macular protocol. Values were analysed related to other subject factors like age and VA. Results All measurements were highly reproducible. The ICCs ranged from 0.823 to 0.992 using macular volume cube. Mean COV was 1.4 ±1.09% (ranged from 0.7 to 1.9%) for the nine ETDRS areas. COV values increased with age; a significant correlation was found between them (r=0.300, p≤0.001). COVs were also related to VA. Conclusion Retinal thickness measurements obtained using Cirrus Fourier‐domain OCT show good reproducibility for healthy eyes. Repeatability is related to the subject age. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index