| Autor: |
Badulescu, Oana Viola, Sirbu, Paul Dan, Filip, Nina, Bordeianu, Gabriela, Cojocaru, Elena, Budacu, Cristian Constantin, Badescu, Minerva Codruta, Bararu-Bojan, Iris, Veliceasa, Bogdan, Ciocoiu, Manuela |
| Předmět: |
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| Zdroj: |
Healthcare (2227-9032); Jun2022, Vol. 10 Issue 6, p993-993, 14p |
| Abstrakt: |
Thrombophilia, also called hypercoagulability or prothrombotic condition, usually reflects a certain imbalance that occurs either in the coagulation cascade or in the anticoagulation/fibrinolytic system. A similar imbalance may be induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Thrombotic complications are associated with multiorgan failure and increased mortality. In this context, activation of coagulation and thrombocytopenia appeared as prognostic markers in COVID-19. Our work provides a structured and updated analysis of inherited thrombophilia and its involvement in COVID-19, emphasizing the importance of diagnosing and initiating thromboprophylaxis. Since the state of hypercoagulation is directly correlated with COVID-19, we consider that studies on the genetic profiles of proteins involved in thrombophilia in patients who have had COVID-19 and thrombotic events are of great importance, both in treating and in preventing deaths due to COVID-19. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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