| Autor: |
Parastesh, Mohammad, Bayatiani, Mohammadreza, Khaleghi, Mina, Shahi, Mohammadreza Sadeghian, Tafti, Farahnaz Ayatizadeh, Aria, Behzad |
| Předmět: |
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| Zdroj: |
Journal of Basic Research in Medical Sciences; 2022, Vol. 9 Issue 1, p10-18, 9p |
| Abstrakt: |
Introduction: One of the famous cancer treatments that are associated with an increment in inflammatory factors is X-ray radiation. This study aimed to evaluate the effect of high-intensity interval training on inflammatory markers in male rats undergoing X-ray radiation. Materials and Methods: In this experimental study, 24 male rats were randomly divided into 4 groups: healthy control (n=6), HIIT (n=6), X-ray radiation (n=6) and X-ray radiation + HIIT (n=6). first, X-ray radiation and HIIT + X-ray radiation groups were anesthetized with ketamine xylazine solution (K, 60-90 kg/mg; Z, 6-10 kg/mg) and then placed on a 1 cm thick Plexiglas plate. The X-ray radiation photon beam was performed using X-ray with 4 Gy linear accelerators (Elekta Compact 6- MV China). The training program included ten weeks of HIIT. Serum levels of Tumor Necrosis Factor Alpha (TNF-α) and Interleukin-6 (IL-6) were measured by rat ELISA Kits. One-way ANOVA was used to determine the existence of a significant difference among groups. Results: The results showed a significant difference between TNF-α and IL-6 in the HIIT, X-ray radiation, and HIIT + X-ray radiation groups with the control group (P < 0.05), but there was no significant difference between these three groups (P > 0.05). Conclusion: X-ray radiation can increase TNF-α and IL-6. HIIT, on the other hand, can also enhance these factors. It seems better for people undergoing radiotherapy to use another exercise training instead of HIIT. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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