Abstrakt: |
Additionally, she developed increased level of tacrolimus following concomitant administration of itraconazole for antifungal prophylaxis and immunosuppressive therapy with tacrolimus [ I not all indications routes and dosage stated i ]. However, he again experienced nausea and vomiting, Therefore, on post operative day 78, the oral itraconazole solution was replaced with itraconazole tablet 300 mg/day. However, on post operative day 55, the serum concentrations of itraconazole and hydroxy-itraconazole were 240 ng/mL and 358 ng/mL, respectively which was below the target concentration 750 ng/mL as the summation. [Extracted from the article] |