Evaluation of posterior segment ocular parameters in patients with pediatric familial mediterranean fever.

Autor: Tufek, Melek, Aydin, Nihat, Capraz, Mustafa, Nalcacioglu, Pinar, Akalin, Irfan
Předmět:
Zdroj: Annals of Medical of Research; Apr2022, Vol. 29 Issue 4, p310-314, 5p
Abstrakt: Aim: We aimed to compare the ocular posterior segment parameters in pediatric patients with Familial Mediterranean Fever (FMF) with a healthy control group. Materials and Methods: We evaluated 40 pediatric FMF patients and 36 healthy children in this study. Choroidal thicknesses from the sub foveal, nasal and temporal 500 µm, 1000 µm, and 1500 µm points; the sub foveal macular thickness; macular volume; optic nerve head (ONH) parameters; and peripapillary retinal nerve fiber layer (RNFL) thickness were measured. An optical coherence tomography (OCT) device was used for measurements. Results: The choroidal thickness in the temporal 1500 µm was significantly thinner, and average peripapillary RNFL thickness was significantly lower in the FMF group compared to the control group (p = 0.015 and p = 0.023, respectively). The groups were similar in terms of macular thickness and macular volume. Among the ONH parameters, the rim area thickness was also significantly higher in the FMF group (p = 0.013). Conclusion: This study shows that the recurrent inflammation caused by FMF can affect choroidal thickness and peripapillary RNFL in children. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index