การตั้งสูตรตำ�รับเจลจากสารสกัดเปลือกบอระเพ็ดสำ�หรับสิวอักเสบ

Autor: อินประเสริฐ, แสงเพ็ญ, แซ่เฮ้ง, พิทักษ์, เพชรี, เพชรพงศ์, เดชบำ�รุง, พิรุณรัตน์, อนันตวุฒิกุล, กฤษดา, นิวัติศัยวงศ์, นวลศรี, ซื่อดี, อารีรัตน์
Předmět:
Zdroj: Journal of Science & Technology MSU; Mar/Apr2022, Vol. 41 Issue 2, p103-116, 14p
Abstrakt: Tinospora crispa (L.) Miers ex Hook. f. & Thomson has been widely used for a long time. The study showed that active ingradients from stem of T. crispa contain anti-inflammatory activity. The purpose of this quatitative research was to compare maceration and soxhlet extraction methods in the extraction of bark from T. crispa with 95% ethanol and to develop gel formulation with T. crispa ethanolic extract for inflammatory acne. The extract was analyzed by UV-VIS spectrophotometer at wavelength 292 and 319 nanometer. Then, the extract was developed into gel formulations which were determined physical properties, chemical properties and stability tests by freeze thaw cycles. The results showed that the T. crispa extract with maceration method and soxhlet extraction method had %yield (w/w) 18.81 and 11.05, respectively. The difference of %yield was 7.76. Therefore, the researcher used the bark T. crispa extract by maceration method to prepare gel formulation with 5% crude extract of T. crispa which were conducted stability tests. The results presented the stability of both gel formulations from T. crispa extract with 0.5% and 1% Carbopol® 940. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index