| Autor: |
Lapetaje, Jerson E., Young, Claire M., Shu, Chang, Smith, Andrew D. |
| Předmět: |
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| Zdroj: |
Chemical Communications; 6/21/2022, Vol. 58 Issue 49, p6886-6889, 4p |
| Abstrakt: |
The isothiourea-catalyzed formal enantioselective conjugate addition of 2-hydroxybenzophenone imine derivatives to α,β-unsaturated para-nitrophenyl esters has been developed. Investigations of the scope and limitations of this procedure showed that β-electron withdrawing substituents within the α,β-unsaturated ester component are required for good product yield, giving rise to a range of β-imino ester and amide derivatives in moderate to good isolated yields with excellent enantioselectivity (20 examples, up to 81% yield and 97 : 3 er). [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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