| Autor: |
Vatkar, Arvind, Kale, Sachin Y., Mehra, Shivam, Bhor, Pramod, Gunjotikar, Aditya, Isaacs, Nikhil R. |
| Předmět: |
|
| Zdroj: |
Journal of Research & Practice on the Musculoskeletal System (JRPMS); Mar2022, Vol. 6 Issue 1, p14-19, 6p |
| Abstrakt: |
Xeroderma Pigmentosa (XP) is an autosomal recessive genetic disorder which causes defective gene repair. This makes XP patients cancer-prone and immunodeficient. A 10-year-old male child with XP was infected with MDR Tubercular Osteomyelitis of sternum. He had constitutional symptoms of TB like weight loss and loss of appetite. He had also developed an abscess in his right pectoral muscles. MRI was done to find out exact location and spread of infection. The abscess was aspirated by Z technique and sent for a Gene Xpert test. Patient was started on second line of anti-tubercular therapy. MDR TB is a growing challenge to treat with anti-tubercular therapy. The link of genetic disorders like XP and infections like TB (which increase in immuno-deficient subjects) needs to be studied further. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
