| Autor: |
Xu, Gui-Qing, Ma, Xue-Ning, Jia, Xian-Bin, Dong, Ya-Hao, Jiang, Yu-Qin, Li, Xin-Juan |
| Předmět: |
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| Zdroj: |
Green Chemistry; 6/7/2022, Vol. 24 Issue 11, p4573-4580, 8p |
| Abstrakt: |
It is of great significance to efficiently synthesize compounds with pharmacological activities through CO2 conversion. Herein, polyionic liquids (PILs) with adjustable structures and multiple active sites were synthesized. With epoxy nucleoside as a solid substrate, cycloaddition and carbonate hydrolysis were carried out under the catalysis of polyionic liquid and the participation of CO2 and water. The amphiphilicity of P1, the adjustability of alkalinity and the regulation of the phase state in the presence of water played an important role in the high selectivity and high yield of the reaction. More importantly, the catalyst can be recycled 6 times to maintain high catalytic activity and selectivity. This work successfully provides a solvent-free, metal-free and recyclable green synthetic path for chiral drugs, which will further promote the highly efficient conversion and utilization of CO2. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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