| Autor: |
Karaali, Müge Göre, Özdemir, Şevki |
| Předmět: |
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| Zdroj: |
Journal of the Turkish Academy of Dermatology; 2022, Vol. 16 Issue 2, p36-40, 5p |
| Abstrakt: |
Background: Corns and calluses are localized plaques of hyperkeratotic tissue over sites that are subjected to continual trauma. In this study, we aimed to investigate the presence of metabolic syndrome (MS) in patients suffering from plantar callosities. Materials and Methods: Between February-December 2021, 32 patients with plantar callosities and 36 healthy subjects frequency-matched for age and sex were included in the study, which was designed as a prospective controlled study. Demographic, clinical and biochemical characteristics of the patients and the controls were recorded. Results: Thirty-two patients with a mean age of 40.56±13.87 years and sex-age-matched 36 healthy controls with a mean age of 41.25±13.15 years were enrolled in the study. MS was present in 59.4% of the patient group. Hypertension (HT) was present in 28.1% of the patient group. Presence of MS and HT were significantly higher in the patient group than the control group (p<0.05). Waist circumference, triglyceride, fasting insulin and Homeostatic model assessment of insulin resistance levels were significantly higher in the patient group than in the control group (p<0.05). HDL cholesterol levels were significantly lower in the patient group that in the control group (p<0.05). It was determined that MS was more common in male patients and patients with unilateral lesion (p<0.05). The number of callosities in patients with MS was lower than in patients without MS (p<0.05). Conclusion: Evaluation of MS may be recommended in patients diagnosed with corns and calluses. Studies about molecular mechanism of callus formation and common mechanisms with MS are needed to elucidate the pathogenesis of callus formation. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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