Synthesis of Novel Pyrazolyl-1,3,4-Thiadiazole Analogues.

Autor: Ningaiah, Srikantamurthy, Bhadraiah, Umesha K., Sobha, Anjali, Shridevi, Doddamani
Předmět:
Zdroj: Polycyclic Aromatic Compounds; 2022, Vol. 42 Issue 4, p1249-1259, 11p
Abstrakt: In the present study, we have designed a novel series of pyrazolyl-1,3,4-thiadiazole analogues by accommodating 1,3,4-thiadiazole ring at C – 4 of pyrazole ring with and without an amide linkage; 5-methyl-1,3-diphenyl-N-(5-phenyl-1,3,4-thiadiazol-2-yl)-1H-pyrazole-4-carboxamide and 2-(5-methyl-1,3-diphenyl-1H-pyrazol-4-yl)-5-phenyl-1,3,4-thiadiazole respectively. We have designed this class of heterocycles by keeping a wide audience in mind, which augment their scientific knowledge. Newly synthesized compounds were characterized by 1H NMR, 13C NMR, mass, IR spectral studies. Single crystal X-ray analysis of some compounds also gave insight into the structural information. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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