| Autor: |
Shah, Nupur, Chhabaria, Siddharth, Dadhia, Bhavin, Soni, Naresh, Jani, Rutu |
| Předmět: |
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| Zdroj: |
Journal of Ahmedabad Dental College & Hospital (JADCH); 2020, Vol. 10, p42-47, 6p |
| Abstrakt: |
Background: Oral submucous fibrosis (OSMF) is a chronic insidious collagen-related disorder associated with betel quid chewing and characterized by progressive hyalinization of the submucosa. It is a well-recognized potentially malignant condition of the oral and oropharyngeal mucosa with initial inflammation followed by progressive fibrosis of the underlying connective tissues. Its treatment is not yet fully standardized, although one of the medical treatment is intralesional injections of steroids or placental extract (Placentrax). Aims and Objectives: The objective of the study was to evaluate the efficacy of intralesional injections of Placentrax in various stages of OSMF. Study Design: The study sample consisted of 8 OSMF patients with various clinical stages of Jani YY and Dudhia BB's staging system. Materials & Methods: Patients received 2 ml of intralesional Placentrax injection, weekly intervals of 5 weeks. Treatment outcome was evaluated on the basis of improvement in trismus and reduction in burning sensation. Results: Improvements were found in trismus and burning sensation. Conclusion: Intralesional placental extract acts as a biogenic stimulant, it is cost-effective and improves the condition with minimal side-effects. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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