ASSESSMENT OF TRANSCRANIAL DUPLEX IMAGING ABNORMALITIES IN EGYPTIAN CHILDREN WITH SICKLE CELL DISEASE.

Autor: Hassab, Hoda, Hanafi, Marwa, Elbeheiry, Ahmed, Hassan, Mona, Ramadan, Mohamed, Chazli, Yasmine El
Předmět:
Zdroj: Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2021, Vol. 12 Issue 3, p1602-1612, 11p
Abstrakt: Stroke has been recognized as a catastrophic clinical manifestation of sickle cell disease SCD, and efforts have been made to identify and treat children at the highest risk. TCD screening has modified the natural history of stroke in children with SCD and emerged as a powerful tool for assessing stroke risk in SCD patients. This cross-sectional study assessed transcranial Doppler imaging (TCDI) velocities in pediatric patients with SCD to identify patients at risk for stroke. Forty-six SCD patients were enrolled (23 males and 23 females), with a median age of 11 years (7.3 - 13.6 years). Thirty-three (71.7%) patients had homozygous SCD, while 28.3% were sickle β-thalassemia. Forty-two (91.3%) patients had normal TCDI findings, and 4 (8.7%) patients had abnormal TCDI findings, including 2.2% of patients who had a conditional TAMMV, while it was low in 6.5% of patients. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index