| Autor: |
JAFFER, SYED, FATIMA, RAKIYA, PAVANI, V., KONERU, ANUPAMA, KRISHNA, LANKA |
| Předmět: |
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| Zdroj: |
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2021, Vol. 12 Issue 3, p2075-2085, 11p |
| Abstrakt: |
Aim: The aim of this study was to determine adverse drug reactions and drug-drug interactions due to polypharmacy in elderly patients on cardiovascular drugs. Method: A prospective observational study was conducted among geriatric patients aged above 60. The study was conducted in the department of cardiology of a tertiary care centre. Prescriptions of 100 elderly patients were analysed for patient demographic details like age, gender, comorbidities, and drugs prescribed. Adverse drug reactions, and drug -drug interactions were assessed using Medscape. Results: In this study, polypharmacy was found in 92 (92%) prescriptions, 72 (72%) prescriptions had drug-drug interactions. 3 (3%) prescriptions had adverse drug reactions. There was an increase in the use of 5-8 medications between ages 60 and 89. Women experienced greater polypharmacy. Conclusion: The finding of present study reveals that there is a positive correlation between age and number of drugs prescribed and women experienced greater polypharmacy. It is found that polypharmacy increases the risk of adverse drug reaction and drug-drug interaction, which can be minimized by pharmacokinetic and pharmacodynamics modification of the drug regimen. Cautionary guidelines can be developed and implemented and also computer-based screening, patient education might help to prevent adverse drug reactions and drug-drug interactions due to polypharmacy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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