| Autor: |
Athokpam, Debina Chanu, Haobam, Sunita, Singh, Khaidem Mani, Chongtham, Urvashi |
| Předmět: |
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| Zdroj: |
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2022, Vol. 13 Issue 1, p412-422, 11p |
| Abstrakt: |
Background:The global incidence of Candidiasis has risen steadily over the past few decades. There is an increase in the incidence of Candida infections due to indiscriminate use and misuse of antibiotics, immunocompromised conditions, prolonged hospital stay and increased use of intravascular devices. Moreover, many studies have reported that the Candida albicans has now been replaced by NAC spp. and there is an increase in resistance to commonly used antifungal drugs. Objective: The present study was taken up to speciate all the Candida isolates from various clinical specimen by conventional method and HiCHROME Agar.Material and Methods:A total of 100 Candida isolates obtained from various clinical specimens were speciated using conventional methods (germ tube test, chlamydospores formation on CMA, sugar fermentation test and sugar assimilation test), HiCHROME agar. Results:The present study showed that Candida infection can occur in all ages. The maximum isolates were obtained from > 70 years of age accounting for 27% of the total isolates. There was a female preponderance with Male:Female ratio of 1:1.3.The most common predisposing factor was found to be prolonged use of antibiotics (25%) followed by patients with diabetes mellitus (21%). NAC (56%) predominated over Candida albicans (44%). The most common NAC spp. was found to be Candida tropicalis (32%) followed by Candida gulliermondi (6%), Candida krusei (5%).Conclusion:The present study shows that NAC spp. predominates over Candida albicans Therefore, speciation will help in knowing the prevalence of Candida species and giving appropriate therapy and prevention. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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