| Autor: |
K., Sharath Babu, Raju, Rathan, Ingale, Arun, Kuradagi, Vinayak |
| Předmět: |
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| Zdroj: |
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2021, Vol. 12 Issue 6, p1191-1196, 6p |
| Abstrakt: |
Background: Surgical removal of allergic fungal mucin is the main stay of treatment. Recurrence rate following functional endoscopic surgery found to be more, which made the introduction of post-operative adjunctive therapy. Medical therapy includes systemic and topical steroids, systemic and topical antifungals and immunotherapy. Steroid is considered as standard medical treatment for AFRS. It reduces the recurrence along with reduction in mucosal changes and systemic IgElevels. But long term use of steroids causes unavoidable systemic toxicity. Our study intends to compare the efficacy of steroid and Itraconazole in preventing recurrence in patients with AFRS in post-operativeperiod. Aims and Objectives: To determine the effect of both drugs on absolute eosinophil count, serum IgE and mucosal changes of nose and paranasal sinuses post operatively. Materials and Methods: One group (Group A) was given oral Itraconazole100mg BD for 6 months post operatively. Steroid (Tab. Prednisolone 30mg OD for one month followed by topical steroids for five months after surgery) was given for the other group (Group B). Results: Both drugs were quiet effective Conclusion: Post-op DNE was better in Itraconazole group. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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