A Study of Fasting Serum Magnesium Levels in Patients with Type2 Diabetes Mellitus in Relation to its Complications.

Autor: Sadhashiv, Kukatla, Reddy, K. Pranay, Pavani, N., Kumar, Danthuri Sharath
Předmět:
Zdroj: Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2022, Vol. 13 Issue 4, p40-46, 7p
Abstrakt: Introduction: Diabetes mellitus is a metabolic disorder with complications including micro & macrovascular. Hypomagnesaemia alters the glucose transport, and decreases the insulin secretion, affects the post receptor insulin signaling and interactions. The aim of our study was to know the relationship between magnesium levels and diabetes, association with level of control of diabetes and magnesium levels in relation to complications of diabetes. Methods: It was a hospital based comparative study where a total of 110 patients were included in the study where 75 Patients with type 2 DM and 35 controls admitted to Gandhi hospital were selected. Basic demographic data was collected and patients were subjected to relevant investigations including serum magnesium levels. RESULTs: Infections were the most common cause for admission accounting for 61.3% of admissions among diabetics. The mean serum magnesium levels in cases and controls was 1.62 mg/dl and 2.31 mg/dl with a P value of <0.003, which was statistically significant. This could probably be explained on the basis of increase urinary loss, low dietary intake. Hypomagnesemia was seen in 44% of the cases where as only 2% of the controls had Hypomagnesemia. Hypomagnesaemia was associated with diabetic retinopathy and diabetic nephropathy. No correlation was found in respect to Neuropathy & IHD. CONCLUSIONs: Hypomagnesaemia is a factor in type 2 diabetes and associated with various complications and duration of diabetes leading to various complications. Hence it is worth measuring serum magnesium levels in patients with type 2 DM and probably correlates their relationship with various complications. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index