Solitary bone metastasis in the tibia as a presenting sign of endometrial adenocarcinoma: a case report and the review of the literature.

Autor: Kaya, Ahmet, Olmezoglu, Ali, Eren, Cemal Suat, Bayol, Umit, Altay, Taskin, Karapinar, Levent, Ozturk, Hasan, Oztekin, Deniz, Guvenli, Yalcin, Karadogan, Ilker
Zdroj: Clinical & Experimental Metastasis; Apr2007, Vol. 24 Issue 2, p87-92, 6p
Abstrakt: Background: Metastasis to bone from endometrial adenocarcinoma is rare, when metastasises it usually locates in axial skeleton. Metastasis to extremities is extremely rare. Additionally the detection of the bone metastasis as a presenting feature is uncommon. In the present study we report the 10th cases of bone metastasis in the literature which located at tibial diaphysis and originated from endometrial adenocarcinoma as a presenting feature of the primary disease. Case: Single tibial lesion was observed in a 70 years old woman. Biopsy confirmed metastatic adenocarcinoma of the unknown origin. We couldn’t find the primary origin with aggressive work-up. Tibial lesion regressed with radiotherapy. Endometrial adenocarcinoma is detected after the end of disease-free one year with the symptom of vaginal bleeding. After 47 months from initial tibial lesion and 35 months from gynaecologic operation, patient is still alive and disease free. Discussion: Patients with endometrial adenocarcinoma presenting an isolated skeletal metastasis may exhibit an unusual group with a better prognosis. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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