| Abstrakt: |
The article focuses on arthropod-borne diseases like plague, typhus, relapsing fevers, and Lyme disease, which mystified millions of people until their causative agents and their relationships to the respective arthropod vectors were established. Early studies of arthropod-borne borrelioses provided an understanding of the sequences taking place in the development of spirochetes in their vectors. However, questions about the interactions between these fascinating microorganisms and their vertebrate hosts, including humans, remained unanswered. It was realized early on that the physiology of spirochetes could not be studied by conventional microscopy alone, instead, more advanced methods were required, such as transmission and scanning electron microscopy and immunochemical, molecular, and genetic procedures. |
Full text from SpringerLink