| Autor: |
Malak, John A., Kurban, Amal K. |
| Předmět: |
|
| Zdroj: |
British Journal of Dermatology; Jun1971, Vol. 84 Issue 6, p516-522, 7p |
| Abstrakt: |
Attention is focused on an excretory function of the epidermis, for which the term ‘catharsis’ is proposed. In this context, the epidermis is viewed as an organ participating actively in the percutaneous elimination of materials from the system. This phenomenon involves the phagocytic activity of epidermal cells, selective uptake, and epidermal proliferation. The particular modus operandi is conceivably dependent on the size and nature of the material to be disposed of. Phagocytosis is operative in certain pathological conditions such as cutaneous leishmaniasis. Selective epidermal uptake occurs in the elimination of certain chemicals. Epidermal proliferation, engulfment and eventual trans-epithelial elimination is seen in elastosis perforans serpiginosa, reactive perforating collagenosis and calcinosis cutis. This mechanism is also observed to a certain extent in the skin lesions of a variety of other conditions such as tuberculosis and North American blastomycosis. The phenomenon of catharsis is regarded as another feature of the intimate dermo-epidermal interplay and interaction. Some of the factors involved in this interaction are reviewed. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Plný text