Granulocyte colony-stimulating factor as a cause of acute leucocytoclastic vasculitis with anti-Ro and anti-La antibodies.

Autor: Ji-Xu, Antonio, Carroll, Liam, Bentley, Thomas, Jarrett, Rachael
Zdroj: BMJ Case Reports; Apr2022, Vol. 15 Issue 4, p1-3, 3p
Abstrakt: Granulocyte colony-stimulating factor (G-CSF) administration is associated with a diverse range of cutaneous sequelae. Serious dermatological side effects of G-CSF include the development of Sweet’s syndrome and exacerbations of pre-existing inflammatory disorders such as psoriasis. Here, we describe a report of acute leucocytoclastic vasculitis caused by G-CSF therapy associated with anti-Ro and anti-La antibodies in a patient with multiple myeloma. This case highlights the importance of having a high index of suspicion for acute leucocytoclastic vasculitis in patients with haematological malignancies undergoing G-CSF therapy. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index