Synthesis and anti-inflammatory activity of N′-substituted 2-[2-(diarylmethylene)hydrazinyl]-5,5-dimethyl-4-oxohex-2-enehydrazides.

Autor:	Siutkina, A. I., Sharavyeva, Yu. O., Chashchina, S. V., Shipilovskikh, S. A., Igidov, N. M.
Předmět:	ANTI-inflammatory agents NUCLEAR magnetic resonance spectroscopy HYDRAZIDES ELEMENTAL analysis ACID derivatives
Zdroj:	Russian Chemical Bulletin; Mar2022, Vol. 71 Issue 3, p496-501, 6p
Abstrakt:	New N′-substituted 2-(2-(diarylmethylene)hydrazinyl)-5,5-dimethyl-4-oxohex-2-enehydrazides were synthesized by the ring opening reaction of 3-diarylmethylenehydrazono-5-tert-butyl-3H-furan-2-ones under the action of aliphatic, aromatic, and heterocyclic acid hydrazides. The structures of the obtained compounds were confirmed by 1H and 13C NMR spectroscopy, IR spectroscopy, and elemental analysis. Their anti-inflammatory activity was studied. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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