| Autor: |
Ginting, Heri Krisnata, Arfijanto, M. Vitanata, Asmarawati, Tri Pudy, Bintoro, S. Ugroseno Yudho |
| Předmět: |
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| Zdroj: |
Indian Journal of Forensic Medicine & Toxicology; Jan-Mar2022, Vol. 16 Issue 1, p589-597, 9p |
| Abstrakt: |
This study was conducted to prove the relationship between the neutrophil-lymphocyte ratio and the severity of COVID-19. A retrospective cohort study using medical record data of inpatients from June to July 2020. Analysis of the NLR relationship and the degree of severity using the Mann Whitney test if the data had an abnormal distribution. Significant if p<0.05 and 95% confidence interval. If there were significant results, we try to measure the cut-off of NLR value to predict severe and non-severe clinical symptoms. Total study subjects were 110 patients, with a male as many as 65 (59.1%), the median age was 53.5 years (range 20-88). Most of the comorbidities were diabetes mellitus (35.5%), followed by hypertension (30%). The severity of clinical symptoms was 50% in the non-severe and severe groups, respectively. The NLR value was higher in the severe group. Mann-Whitney test showed significant differences in the value of NLR between the severe group and the not severe group with the p-value <0.001. Receiver operating characteristic (ROC) curve analysis area under the curve (AUC) of NLR on day-1 was 0.716 (CI 95%: 0.605 - 0.826), and the cut-off point of the prediction severity disease at day-7 was = 6.14 with a sensitivity of 71% and a specificity of 69.1%. The neutrophil-lymphocyte ratio value with severe symptoms was higher than the neutrophil ratio value for lymphocytes with nonsevere symptoms in patients with COVID-19. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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