Synthesis of α‐Ketoamides via Electrochemical Decarboxylative Acylation of Isocyanides Using α‐Ketoacids as an Acyl Source.

Autor: Zhao, Yuhan, Meng, Xia, Cai, Changqun, Wang, Lingyun, Gong, Hang
Předmět:
Zdroj: Asian Journal of Organic Chemistry; Apr2022, Vol. 11 Issue 4, p1-5, 5p
Abstrakt: A catalyst‐, transition metal‐, oxidant‐free strategy for the synthesis of α‐ketoamides via an electrochemical decarboxylative acylation of isocyanides at room temperature with carbon dioxide as a sole by‐product was developed in this work. This is a simple, rapid and practical strategy under mild conditions for synthesizing highly functionalized α‐ketoamides with high atom economy. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index