| Autor: |
Omori, Reina, Miyagaki, Tomomitsu, Kubo, Marie, Komaki, Reo, Kishi, Arisa, Kuroda, Eri, Okudaira, Azusa, Ohashi, Hiroyuki, Takeuchi, Sora, Koga, Hiroshi, Ishii, Norito, Kadono, Takefumi |
| Předmět: |
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| Zdroj: |
International Journal of Dermatology; May2022, Vol. 61 Issue 5, pe184-e186, 3p |
| Abstrakt: |
Dear Editor, It has been widely known that dipeptidyl peptidase-IV inhibitors (DPP4i) are causative factors of bullous pemphigoid (BP). Anti-laminin-332 antibody usually causes mucous membrane pemphigoid, whereas there have been some conventional pemphigoid cases with anti-laminin-332 antibody showing only skin lesions like our case.5 Although our single case experience cannot make a conclusion, anti-laminin-332 antibody in DPP4i-associated BP might also be associated with an inflammatory phenotype. Anti-BP230 antibody was detected in some DPP4i-associated BP patients in coexistence with the antibody to full-length BP180,4 while only one case of DPP4i-associated BP solely positive for anti-BP230 antibody has been reported.2 That case showed blisters with surrounding erythema similar to our case, suggesting that anti-BP230 antibody might be associated with an inflammatory phenotype in DPP4i-associated BP. [Extracted from the article] |
| Databáze: |
Complementary Index |
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