Congenital Heart Defects in Patients with Classic Bladder Exstrophy: A Hitherto Neglected Association?

Autor: Promm, Martin, Gerling, Stephan, Schepp, Carsten P., Rösch, Wolfgang H.
Předmět:
Zdroj: European Journal of Pediatric Surgery; Apr2022, Vol. 32 Issue 2, p206-209, 4p
Abstrakt: Introduction:  Classic bladder exstrophy (BE) is regarded as an isolated malformation without any further anomalies, but some studies have indicated a higher incidence of cardiac anomalies. This cross-sectional study is planned to evaluate the prevalence of congenital heart defects (CHDs) and the clinical relevance for patients with BE admitted for primary closure.Materials and Methods:  Patients were prospectively recruited between March 2012 and January 2019. Patients' profiles including demographic data, results of transthoracic echocardiography (TTE), as well as essential peri- and postoperative data were assessed.Results:  Thirty-nine (25 boys and 14 girls) patients with BE (median age 61 days) underwent delayed primary bladder closure. Thirty-seven (24 boys and 13 girls) patients had received TTE 1 day before surgery. CHD was detected in 7 (18.9%) out of the 39 patients, but no clinical differences between patients with and without CHD were observed peri- or postoperatively.Discussion and Conclusion:  This prospective systematic evaluation shows an even higher rate of CHD in patients with BE than assumed previously. Although peri- and postoperative outcome did not differ between patients with and without CHD, we consider TTE an important additional method for ensuring a safe peri- and postoperative courses and a short- and long-term care for patients with CHD. [ABSTRACT FROM AUTHOR]
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