Expression and distribution of cell-surface proteoglycans in the normal Lewis rat molar periodontium.

Autor: Worapamorn, W., Li, H., Pujic, Z., Xiao, Y., Young, W.G., Bartold, P.M.
Předmět:
Zdroj: Journal of Periodontal Research; Aug2000, Vol. 35 Issue 4, p214-224, 11p
Abstrakt: Cell-surface proteoglycans participate in several biological functions such as cell-cell and cell-matrix interactions, cell adhesion, the binding to various growth factors as co-receptors and repair. To understand better the expression and distribution of cell-surface proteoglycans in the periodontal tissues, an immunohistochemical evaluation of the normal Lewis rat molar periodontium using panels of antibodies for syndecan-1, -2, -4, glycan and betaglycan was carried out. Our results demonstrated the expression and distribution of all proteoglycans compartments. The presence of these cell-surface proteoglycans indicates the potential for roles in the process of tissue homeostasis, repair or regeneration in period periodontium of which each function requires further study. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index