Neurophysiological Correlates of Impaired Development in Autism Spectrum Disorder (ASD).

Autor: Salimova, K. R.
Zdroj: Biology Bulletin Reviews; Apr2022, Vol. 12 Issue 2, p140-148, 9p
Abstrakt: Autism spectrum disorder (ASD) is a large group of developmental disorders caused by a combination of genetic and environmental factors. It is described as a separate diagnosis in the 11th revision of the International Classification of Diseases. Forms of the disorder are distinguished based on the existing intellectual and language deficits. The problem is relevant due to ASD wide distribution (about 1% of the general population) and difficulties in the social rehabilitation of such people. Neurophysiological studies of this heterogeneous group revealed various impairments of ontogenetic formation of electroencephalogram (EEG) patterns. Some of the main autistic features, such as social isolation and inability to empathize, can be attributed to dysfunctional mirror neurons. The article reviews studies of the age-related formation of EEG in a normal group, as well as the EEGs of undifferentiated ASD. It also discusses in detail mechanisms of dysfunction of mirror neuron system in these disorders. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index