| Autor: |
Lacaze, Paul A, Tiller, Jane, Winship, Ingrid, Lacaze, Paul, Brotchie, Adam, McNeil, John, Zalcberg, John, Thomas, David, Milne, Roger, James, Paul, Delatycki, Martin, Young, Mary‐Anne, Nowak, Kristen, Nguyen‐Dumont, Tu, Southey, Melissa, Ademi, Zanfina, Bruinsma, Fiona, Riaz, Moeen, Terrill, Bronwyn, Kirk, Judy |
| Předmět: |
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| Zdroj: |
Medical Journal of Australia; Apr2022, Vol. 216 Issue 6, p278-280, 3p |
| Abstrakt: |
Our previously published health economic modelling studies of DNA screening for HBOC, Lynch syndrome20 and familial hypercholesterolaemia21 provide a platform for the consideration of DNA screening in Australia. Our model on DNA screening for familial hypercholesterolaemia genes found similar results.21 Our future modelling will assess the combined benefits and costs of screening for familial cancer genes and familial hypercholesterolaemia genes concurrently in the same test. At $200 per test, savings in prevented cancer treatment outweighed DNA screening costs, projecting DNA screening to be cost-saving for the Australian public health system (for cancer genes alone). Keywords: Genetic counselling; Mass screening; Population health EN Genetic counselling Mass screening Population health 278 280 3 04/05/22 20220401 NES 220401 Australia will take a world-first step towards offering preventive DNA screening through the public health care system In adult-onset genomic conditions, such as hereditary breast and ovarian cancer (HBOC), Lynch syndrome and familial hypercholesterolaemia, certain DNA variants confer high risk of developing future disease.1 DNA screening for these conditions could thereby identify medically actionable genetic risk factors, prompting timely risk management and informed decision making from early adulthood to facilitate early detection or prevention.2 Despite this opportunity, diagnostic rates for these conditions remain low,2-4 limited by restricted access to genetic testing and lack of awareness. [Extracted from the article] |
| Databáze: |
Complementary Index |
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