Ethambutol-induced Bullous Skin Lesions in Mycobacterium kansasii Lung Infection.

Autor: Kollipara, Venkateswara K., Horowitz, Mitchell, Lantz, Jeffery, Nagy-Agren, Stephanie
Zdroj: International Journal of Mycobacteriology; Jan-Mar2022, Vol. 11 Issue 1, p120-122, 3p
Abstrakt: Mycobacterium kansasii is the second most common cause of nontuberculous mycobacterial (NTM) lung disease after Mycobacterium avium complex infection in the United States.[1] The first-line therapy for M. kansasii is a three-drug regimen including rifampin, isoniazid, and ethambutol. We present a case of a patient with pulmonary M. kansasii who developed bullous skin lesions while receiving this regimen and again after rechallenge with ethambutol. In patients with intolerance to one of the first-line antibiotics, a multidisciplinary team approach to starting second-line agents is needed. Ethambutol should be included in the differential diagnosis of drug-induced bullous skin lesions in treated patients with NTM, who develop new onset rash with blisters or ulceration. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index