| Autor: |
Morse, Ryan, Ganju, Rohit G., Chen, Allen M. |
| Předmět: |
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| Zdroj: |
Precision Radiation Oncology; Mar2022, Vol. 6 Issue 1, p39-45, 7p |
| Abstrakt: |
Objective: To analyze patterns of care in radiotherapy field design for patients treated for head and neck squamous cell carcinoma of unknown primary origin in the modern era. Methods: From January 2014 to April 2018, 33 patients were treated by intensity‐modulated radiation therapy for squamous cell carcinoma metastatic to the cervical lymph nodes of unknown primary origin. A total of 17 patients (52%) were treated by primary radiation; 16 (48%) were treated after surgery. N‐classification was N1 (3 patients); N2a (8 patients); N2b (15 patients); N2c (2 patients); and N3 (5 patients). Human papillomavirus status was positive in 19 (58%) and negative in 14 patients (42%). Results: A total of 15 patients (46%) were treated with classic comprehensive fields to the entirety of the pharyngeal mucosal axis and bilateral cervical necks. Seven patients (21%) received ipsilateral neck radiation only. The total mucosal axis was irradiated in 15 patients (46%). Among the entire population, the nasopharynx and larynx were intentionally omitted in 36% and 48%, respectively. None of the clinical parameters predicted for the use of less‐than‐comprehensive radiation fields (P > 0.05, for all). Conclusion: Significant variation exists in the radiotherapeutic management of head and neck unknown primary cancer. Further research to better optimize standards is required. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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