Incidence, Predictors and Outcomes of Noninvasive Ventilation Failure in Very Preterm Infants.
| Autor: | Fernandez-Gonzalez, Sara M., Sucasas Alonso, Andrea, Ogando Martinez, Alicia, Avila-Alvarez, Alejandro |
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| Předmět: |
SURVIVAL
RESPIRATORY insufficiency CEREBRAL hemorrhage CONFIDENCE intervals HEALTH outcome assessment RETROSPECTIVE studies GESTATIONAL age DISEASE incidence ARTIFICIAL respiration RISK assessment DESCRIPTIVE statistics BRONCHOPULMONARY dysplasia DATA analysis software ODDS ratio LONGITUDINAL method |
| Zdroj: | Children; Mar2022, Vol. 9 Issue 3, p426, 10p |
| Abstrakt: | Non-invasive ventilation (NIV) is now considered the first-line treatment for respiratory distress syndrome in preterm infants. We aimed to evaluate the rates of non-invasive ventilation failure rate in very preterm infants, as well as to identify its predictors and associated outcomes. We designed a single-center retrospective cohort study including infants ≤32 weeks gestational age and ≤1500 g. The NIV failure was defined as the need for intubation at <72 h of life. After applying inclusion and exclusion criteria, 154 patients were included in the study, with a mean GA of 29.7 ± two weeks. The NIV failure rate was 16.2% (n = 25) and it was associated with lower bronchopulmonary dysplasia (BPD)-free survival (OR 0.08; 95% CI 0.02–0.32) and higher incidence of intraventricular hemorrhage > II (OR 6.22; 95% CI 1.36–28.3). These infants were significantly smaller in GA and weight. Higher FiO |
| Databáze: | Complementary Index |
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