T regulatory cells from atopic asthmatic individuals show a Th2‐like phenotype.

Autor: Jansen, Kirstin, Satitsuksanoa, Pattraporn, Wirz, Oliver F., Schneider, Stephan R., van de Veen, Willem, Tan, Ge, Sokolowska, Milena, Message, Simon D., Kebadze, Tatiana, Glanville, Nicholas, Mallia, Patrick, Akdis, Cezmi A., Moniuszko, Marcin, Johnston, Sebastian L., Nadeau, Kari, Akdis, Mübeccel
Předmět:
Zdroj: Allergy; Apr2022, Vol. 77 Issue 4, p1320-1324, 5p
Abstrakt: We showed that the expression of CRTH2 and IL-4 on Treg cells is higher in asthmatic individuals compared to controls (Figure 2A). T regulatory cells from atopic asthmatic individuals show a Th2-like phenotype However, under certain conditions, Treg cells can display a pathogenic and proinflammatory phenotype and contribute to disease pathogenesis.2 Treg cells of food allergic children showed a T helper 2 (Th2)-like phenotype. [Extracted from the article]
Databáze: Complementary Index