Acceptance of SARS-CoV-2 vaccination among cancer patients in Portugal: attitudes and associated factors.

Autor:	de Sousa, Maria João, Caramujo, Cecília, Júlio, Neidy, Magalhães, Joana Correia, Basto, Raquel, Fraga, Teresa, Gomes, Inês Ferreira, Monteiro, Ana Raquel, Pazos, Isabel, Sousa, Gabriela
Předmět:	VACCINATION CANCER patient psychology IMMUNIZATION CONFIDENCE intervals ATTITUDE (Psychology) COVID-19 vaccines MULTIPLE regression analysis RURAL conditions PATIENTS' attitudes VACCINE effectiveness QUESTIONNAIRES VACCINE hesitancy DESCRIPTIVE statistics SOCIODEMOGRAPHIC factors INTENTION ODDS ratio RESIDENTIAL patterns EDUCATIONAL attainment
Zdroj:	Supportive Care in Cancer; May2022, Vol. 30 Issue 5, p4565-4570, 6p
Abstrakt:	Objective: COVID-19 vaccines have shown efficacy and safety in healthy people. However, cancer patients under active immunosuppressive treatment were not included in the clinical trials conducted to test vaccines' efficacy and safety. This study aimed to evaluate the COVID-19 vaccine acceptance in cancer patients undergoing immunosuppressive therapy. Methods: A total of 200 adult cancer patients received a questionnaire between March 8 and April 2, 2021, before the beginning of cancer patients' vaccination in Portugal. The questionnaire adapted from previously conducted studies included 11 close-ended items, evaluating variables such as patient sociodemographic and clinical characteristics, and the acceptance and underlying reasons to be or not to be vaccinated. The primary outcome was the intended acceptance of the COVID-19 vaccine in cancer patients. Multiple logistic regression was performed to identify factors associated with intended acceptance. Results: Among the 200 delivered questionnaires, only 169 were included in this study. From those, 142 (84%) patients intended to be vaccinated against COVID-19. Only 27 participants (16%) had not yet decided or were reluctant to COVID-19 vaccination. High school degree (odds ratio (OR) 0.133, 95% confidence interval (C.I.) 0.031–0.579, p = 0.007], rural residence (OR 0.282, 95% C.I. 0.081–0.984, p = 0.047), and reluctance in believing in the vaccine efficacy (OR 0.058, 95% C.I. 0.016–0.204, p < 0.001] were identified predictors factor for COVID-19 vaccine hesitancy. Conclusion: Most patients intended to be vaccinated against COVID-19, and specific factors such as education level, rural residence and the belief in vaccine efficacy were related to vaccine acceptance. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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