Temporal concordance between pulse contour analysis, bioreactance and carotid doppler during rapid preload changes.

Autor: Kenny, Jon-Émile S., Barjaktarevic, Igor, Eibl, Andrew M., Parrotta, Matthew, Long, Bradley F., Elfarnawany, Mai, Eibl, Joseph K.
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Zdroj: PLoS ONE; 3/23/2022, Vol. 17 Issue 3, p1-10, 10p
Abstrakt: Purpose: We describe the temporal concordance of 3 hemodynamic monitors. Materials and methods: Healthy volunteers performed preload changes while simultaneously wearing a non-invasive, pulse-contour stroke volume (SV) monitor, a bioreactance SV monitor and a wireless, wearable Doppler ultrasound patch over the common carotid artery. The sensitivity and specificity for detecting preload change over 3 temporal windows (early, middle and late) was assessed. Results: 40 preload changes were recorded in total (20 increase, 20 decrease). Immediately, the wearable Doppler had high sensitivity (100%) and specificity (100%) for detecting preload change with an area under the receiver operator curve (AUROC) of 0.98 for both velocity time integral (VTI, 10.5% threshold) and corrected flow time (FTc, 2.5% threshold). The sensitivity, specificity and AUROC for non-invasive pulse contour were equally good (9% SV threshold). For bioreactance, a 13% SV threshold immediately detected preload change with a sensitivity, specificity and AUROC of 60%, 95% and 0.75, respectively. After two SV outputs following preload change, the sensitivity, specificity and AUROC of bioreactance improved to 70%, 90% and 0.85, respectively. Conclusions: Carotid Doppler ultrasound and non-invasive pulse contour detected rapid hemodynamic change with equal accuracy; bioreactance improved over time. Algorithm-lag should be considered when interpreting clinical studies. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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