| Autor: |
M., Abdullahi, Ganiyu, Aliyu G., H., Adamu |
| Předmět: |
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| Zdroj: |
Journal of Experimental Research; Dec2021, Vol. 9 Issue 4, p1-7, 7p |
| Abstrakt: |
Microalbuminuria is an independent risk factor for cardiovascular diseases (CVD), and it is now considered as an important emerging target for primary prevention strategies in CVD. Restriction of dietary acid intake has been suggested as one possible effective dietary strategy that might offer significant reductions of microalbuminuria. However, reports from previous studies are conflicting. We investigated whether higher dietary acid intake is associated with greater risk of microalbuminuria in apparently healthy adult Nigerians. We assessed dietary intake using a food frequency questionnaire and the Nigerian Food Composition Table. Acid forming potential of our local diets were estimated as Potential Renal Acid Load (PRAL) scores. Urine albumin and creatinine were measured. Microalbuminuria was defined as urinary albumin-creatinine ratio of 30 - 300mg/g. Across the quartiles of the PRAL scores, there was a statistically significant trend with higher intake of dietary acid associated with increased risk of incident microalbuminuria (for trend < 0.05). We conclude that among the subjects in this study higher intake of dietary acid is associated with significant increased risk of microalbuminuria. We recommend further longitudinal studies that will investigate whether lifestyle modification that include restriction of diet with high acid forming potentials, in the general population or among individuals with cardiovascular risk profile, will be a useful approach in lowering the incidence of microalbuminuria and preventing (and/or delay) cardiovascular diseases in our setting. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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