Combined training in patient with aids: improved quality of life and preserved BDNF.

Autor: Khoramipour, Kayvan, Katanchi, Abbas, Hajirasouli, Masoud, Behbudi, Laleh, Basereh, Aref, Dehghan, Pooneh, Khaled, Mehdi, Chamari, Karim
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Zdroj: Sport Sciences for Health; Mar2022, Vol. 18 Issue 1, p39-46, 8p
Abstrakt: Objectives: This study aims to investigate the impact of combined exercise training on selected health status measures and quality of life in patients with AIDS Material and methods: Thirty AIDS patients were randomly divided into two groups of combined exercise training on one hand and control on the other. Combined training consisted of aerobic and resistance exercises for a duration of 12 weeks (three sessions/week). Aerobic training consisted of walking or running on a treadmill with increasing intensity from 40 to 65% of maximal heart rate for 30–60 min. Resistance sessions were made of leg press, lateral pull down, biceps curl and chest press, with 40–65% of 1-RM, two to four sets of 12–20 repetitions. Blood samples were taken from patients around 24 h before the first and 72 h after the last training sessions and cluster of differentiation four cells (CD4), serum brain-derived neurotrophic factor (BDNF), and viral load levels as well as the quality of life were assessed Results: The results showed that although combined exercise training did not affect CD4 and viral load, quality of life increased significantly in the training group (p = 0.04). Moreover, BDNF significantly decreased in the control group but not in the training group (p = 0.03) Conclusions: These findings suggest that combined exercise training over 3 months resulted in increased quality of life while preventing reductions in BDNF levels in AIDS patients, while no changes in viral load and CD4 count have been noticed [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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